C57bl6 mice the jackson laboratory

The Jackson Laboratory's mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. Our mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health The Jackson Laboratory c57bl 10 mice C57bl 10 Mice, supplied by The Jackson Laboratory, used in various techniques. Bioz Stars score: 88/100, based on 7 PubMed citations C57BL/6, often referred to as C57 black 6, C57 or black 6, is a common inbred strain of laboratory mouse. It is the most widely used genetic background for genetically modified mice for use as models of human disease The Jackson Laboratory c57bl 6j C57bl 6j, supplied by The Jackson Laboratory, used in various techniques. Bioz Stars score: 99/100, based on 705 PubMed citations

The Jackson Laboratory is generating various AD-BXD strains for distribution: Stock No. 032881, Stock No. 032882, Stock No. 032883, Stock No. 032884. For more information about these mice, see the Alzforum News story Physiological Data Summary - C57BL/6J (000664) Revised: December 13, 2007 Complete data with range and standard deviations available from the Mouse Phenome Database. The C57BL/6 strain was brought to The Jackson Laboratory in 1948 (C57BL/6J). C57BL/6JRj show age-related hearing loss and are resistant to audiogenic seizures. This hearing loss is related to the presence of allele Cdh23 ahl (Cadherin 23 age-related hearing loss) Introduction The Jackson Laboratory 1 Th e laboratory mouse is playing an increasingly important role in biomedical research. Due to mutagenesis, transgenic, and. The Jackson Laboratory in Bar Harbor, Maine is currently one of the world's largest suppliers of laboratory mice, at around 3 million mice a year. The laboratory is also the world's source for more than 8,000 strains of genetically defined mice and is home of the Mouse Genome Informatics database

The C57BL/6J mice and C3HeB/FeJ mice were originally purchased from The Jackson Laboratory (Bar Harbor, ME), and the C57BL/6NTac mice were from Taconic (Hudson, NY). The group labeled C57BL/6N contains cohorts of mice on the C57BL/6N background that were originally obtained from various independent providers except Taconic. In cases of mutant line littermates, expansion of the breeding colony. To The Jackson Laboratory from Hall in 1948. To NIH in 1951 from The Jackson Laboratory at F32. To Charles River in 1974 from NIH. Coat Color: Black Produced: North America, Europe and Japan research models. Genetic Management of C57BL/6 Mouse Colony Inb. To The Jackson Laboratory in 1948 from Hall. To NIH in 1951 from The Jackson Laboratory at F32. To Charles River in 1974 from NIH.Model Properties: Coat Color: Black MHC Haplotype: H2b Ideal For: general multipurpose model, diet-induced obesity, transgenic/knockout model development, safety and efficacy testing, immunology Stra.. For example, P2X7 knockout mice (The Jackson Laboratory) were used to study the role of the P2X7 receptor in the repair of in vivo corneal epithelial debridement wounds , and leptin knockout (ob/ob) mice (Jackson Laboratory) were used to determine the effect of O-GlcNAcylation on platelet function Longitudinal and cross sectional healthspan and lifespan studies on C57BL6/J, Diversity Outbred (DO) and Collaborative Cross (CC) and various KOMP strains have been completed or are currently in process. High-throughput phenotyping pipelines have been established for CC and DO mice. The Jackson Aging Center (JAC) has collected and curated thousands of tissue samples from mice representing a.

The Jackson Laboratory

C57BL is probably the most widely used of all inbred strains, (substrain C57BL/6 alone accounts for over 14% of occasions on which an inbred strain is used) though in many ways it seems to be atypical of inbred strains of laboratory mice Laboratory mice are generally docile but will move quickly or jump away from the person trying to restrain them, and some strains may bite. Mice can be moved a short distance for examination by being picked up at the base of the tail and placed onto the top of their cage allowing the mouse to grasp the bars with the forefeet and direct its effort away from the handler. Very obese or pregnant. I asked the almost the same questions differently to Jackson Lab about the difference in size of brain of 6 and 16 week old C57 mice. They said that 4 weeks old mice are having about 5-7% smaller.

MGI: the international database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data for researching human health and disease A Comparison of Diet-Induced Obese Mice From Taconic and the Jackson Laboratory A Comparison of Metabolic Characteristics Among C57BL/6NTAC, C57BL/6J, and C57BL/6JBOM DIO Mice With Environmental Conditionin Since the 1960s, the grounds at the Jackson Laboratory have been divided across the middle, with research and development on one side, closer to the pine-covered mountains, and mouse production on. The Jackson Laboratory's colony was divided in two sub-strains before 1937, resulting in the C57BL/6 and the C57BL/10 strains. The C57BL/6 strain was brought to The Jackson Laboratory in 1948 (C57BL/6J)

为了研究MAPK异常活化可被Ste5构象改变隔绝,采用了Jackson Laboratory的C57BL6 mice进行小鼠杂交实验。 至该文献 为了研究皮肤微生物能够提供保护性免疫,采用了Jackson Laboratory的C57BL/6 specific pathogen-free mice进行动物实验 Taconic received this strain in 1991, and The Jackson Laboratory received theirs in 1997. Taconic maintains the genetic stability of all inbred mouse strains through cryopreservation, ensuring that C57BL/6NTac is as similar as possible to the original C57BL/6N line maintained at the NIH The Jackson Laboratory. Hematological survey of 11 inbred strains of mice. MPD:Jaxpheno4. Mouse Phenome Database website, The Jackson Laboratory, Bar Harbor, Maine, Hematological survey of 11 inbred strains of mice

Click above to download a CSV file that can be opened in Excel. The file contains all strain survey measured phenotypes where C57BL/6J was tested, along. Behavioral Characteristics & Handling. The Jackson Laboratory reports that these mice are more prone to biting when being handled than more docile strains such as.

C57 Mouse. Nomenclature: C57BL/6NCrl. Origin: Developed by C.C. Little in 1921, from a mating of Miss Abby Lathrop's stock that also gave rise to strains C57BR and C57L. Strains 6 and 10 separated about 1937. To The Jackson Laboratory in 1948 from Hall. The Jackson Laboratory's list of inbred strains of mice, which gives the susceptibility of different strains of mice to disease. Guidelines for assessing the condition and health of mice , a pdf file of a paper from Lab Animal Le Jackson Laboratory de Bar Harbor - Courtesy of The Jackson Laboratory Le laboratoire emploie 1200 ouvriers; la plupart d'entre eux sont originaires de Bar Harbor C57BL/6ByJ The Jackson Laboratory (Bar Harbor, Maine, USA) - Genomic DNA of C57BL/6JEiJ, C57BL/6NJ, C57BL/6By and C57BL/6ByJ used for this study were directly purchased from The Jackson Laboratory

C57bl 10 Mice The Jackson Laboratory Bio

  1. A High-Fat Diet Impairs Liver Regeneration in C57BL/6 Mice Through Overexpression of the NF- B Inhibitor, I B RobertA.DeAngelis,1,2 MaciejM.Markiewski,1 RebeccaTaub,2.
  2. The C57BL/6 is one of the most widely used mouse strains in behavioral, pharmacological, and genetic research but little is known about their response on tests for antidepressant drugs
  3. Mice were maintained and cared for in accordance to the National Institutes of Health (NIH) guidelines in our AAALAC-accredited experimental animal facility under controlled environment (21±2 °C.
  4. C57BL/6JOlaHsd mice originate from the Jackson Laboratory, Bar Harbor, Maine. In 1974 to the Laboratory Animal Centre, Carshalton UK. To Olac in 1983 (now Envigo)
  5. is-tration. The p53+/+, p53+/−, and p53−/− C57BL6/J mice were purchased from The Jackson Laboratory..

obtained from The Jackson Laboratory (Bar Harbor, ME), and male and female WT and Alox15 / C57BL6 mice (20-25 g) were provided by Dr. J. L. Nadler of East Virginia Medical School Several laboratories have generated their own, in-house congenic lines by backcrossing to C57BL6 mice. 5xFAD mice on a congenic C57BL/6J background are commercially available through The Jackson Lab (JAX MMRRC Stock# 034848, formerly Jackson Lab Stock# 008730), where the retinal degeneration allele Pde6b rd1 was bred out of the original strain. The Jackson Lab has observed a less-robust.

C57BL/6 - Wikipedi

  1. Male RAG1 −/− mice were purchased from the Jackson Laboratory at 3 weeks old and given free access to chow diets. CD4 + CD45RB HI cells from splenocytes of male C57BL6/J mice (Jackson Laboratory) were isolated by magnetic separation and flow assisted cell sorting ( Ostanin et al., 2009 )
  2. The Jackson Aging Center is accepting applications for Pilot Research Projects in the biology of aging utilizing currently available aged male and female C57BL6/J mice from Jackson's Nathan Shock Center
  3. Mice were purchased from The Jackson Laboratory (Bar Harbor, ME, USA) or where specific strains were used, generated in house at the University of Nevada (Reno, NV, USA) or University of California San Francisco (San Francisco, CA, USA). Several strains.
  4. The Jackson laboratory in Bar Harbor, Maine is currently one of the world's largest suppliers of laboratory mice, at around 3 million mice a year. The laboratory is also the world's source for more than 8,000 strains of genetically defined mice and is home of the Mouse Genome Informatics database
  5. Supporting Information Ribas et al. 10.1073/pnas.1104533108 SI Methods Animals. Lean and obese Lepob C57Bl6 female mice were pur-chased from The Jackson Laboratory at.
  6. Previous studies have shown that NNT mutation causes redox abnormalities in mitochondria and alterations in glucose and lipid metabolism in C57BL6/J mice from The Jackson Laboratory. Metabolic syndrome is characterized by an association of cardio-metabolic disturbances such as visceral obesity, dyslipidemias, glucose intolerance and/or insulin resistance and hypertension. Caloric restriction.
  7. We used 6-8-week-old male C57Bl6/J mice (Jackson Laboratory, Bar Harbor, ME) and CD1dKO mice, which were obtained by backcrossing CD1d null mice (generously provided by Prof. Mattner, Department of Microbiology, Universit€atsklinikum Erlangen, Germany).

Materials and methods mice c57bl6 mice were purchased Materials and Methods Mice C57BL/6 mice were purchased from The Jackson Laboratory (Bar Harbor, ME). C57BL/6 Trail 2 / 2 mice were obtained from Amgen (Seattle, WA). Mekada et al. reported that 30 SNPs differ between BL6J mice from The Jackson Laboratory and BL6N mice from Japan SLC 11 and that the deletion of exons 7-11 in the Nnt gene is detected in BL6J. JAX® Mice bred and distributed from The Jackson Laboratory and Charles River Laboratories in Europe and Japan are bred using established practices that reduce the.

Mouse Alloantigens Major histocompatibility (MHC) is a group of antigens, most of which influence allograft rejec-tion. These antigens can be divided into two major. C57BL6/J mouse-derived fertilized eggs. Founders were identified by PCR. We obtained the Hmga2 mouse line by breeding the Hmga2 founder mouse with C57BL6/J mice (The Jackson Laboratory). Mice were kept in the transgenic barrier facility at Washington Uni. Body Weights • Tac C57BL/6 mice are heavier than Jaxon the HFD • By ANOVA, Group, time and interaction were all highly significant (P<0.0001) The Jackson Laboratory の厳格な基準に基づき日本チャールス・リバー(株)で生産し、2003年4月より国内での生産・供給を開始いたしました。 JAX® Mice生産システムについては、 こちら をご参照ください

C57bl 6j The Jackson Laboratory Bio


  1. Similar results are obtained using C57BL/6 mice from The Jackson Laboratory, as well as with MOG 1-125 /CFA Emulsion PTX using the recommended protocol. Group Mice/grou
  2. C57BL6/J mice were used as host and bone marrow cells for transplantation were prepared from female B6.SJL-Ptprc a Pepc b /Boy (Ly5.1) or female 129S1/SvImJ mice. All mice were obtained from Jackson Laboratories and used at 8 - 10 weeks of age. All experiments were performed using protocols approved by the Memorial Sloan Kettering Cancer Center (MSKCC) Institutional animal care and use.
  3. Male C57BL6 mice >4 months of age were obtained from the Jackson Laboratory (Bar Harbor, ME, USA). Conditional ablation of satellite cells A study design schematic is found in Fig. 1a

The Jackson Laboratory, Charles River Laboratories, Taconic Farms, and Harlan Laboratories are the main suppliers. Major research applications are in immunology, oncology, physiology, pathology, and neuroscience The Jackson Laboratory. University of New Hampshire . University of New Hampshire + de 500 relations. Consultez le profil complet de Kristen Onos. C'est gratuit. Vos collègues, vos amis et plus de 500 millions de professionnels sont sur LinkedIn. S'i. The Jackson Laboratory. Hematological survey of 11 inbred strains of mice. MPD:Jaxpheno4. Mouse Phenome Database website, The Jackson Laboratory, Bar Harbor, Maine, Hematological survey of 11 inbred strains of mice


The effects of VEGF-A on atherosclerosis, lipoprotein profile, and lipoprotein lipase in hyperlipidaemic mouse models Suvi E. Heinonen. 1. Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, University of E. Transplantation of MBECs into irradiated C57Bl6 mice. Eight- to 10-week-old C57Bl6 mice (Jackson Laboratory, Bar Harbor, ME) were irradiated with 700 cGy total body. Mice from the inbred C57BL/6 strain have been commonly used for the generation and analysis of transgenic and knockout animal models. However, several C57BL/6. Laboratory. Donor mice (genotype: C57BL6/J-1 hbd / 1 hbd, Gpi1 a / Gpi1 a) were generated by Dr. Jane Barker at the Jackson Labora-tory by backcrossing of the Gpi1 a locus onto the C57BL/6J back-ground. For the first experiment, normal recipients were 71.

Laboratory mouse - Wikipedi

Animals - C57BL6 mice were from The Jackson Laboratory (Bar Harbor, ME). The Institutional Animal Care and Use Committee at the University of Colorado Denver approved all animal experiments Jackson Laboratory C57BL/6 CBA F1 hybrid mice transgenic mouseはたばこの主流煙にさらされたマウスの心臓におけるプラスミノーゲンアクチベータ抑制因子-1遺伝子の変化のトキシコゲノミクスを用いた解析に使用されています

Clinical Chemistry Reference Intervals for C57BL/6J, C57BL/6N

#018787) were purchased from Jackson Laboratory (Bar Harbor, ME, USA) and housed at the Emory University animal facility. These mice were fed ad libitum with standard cho were maintained on a mixed C57Bl6/Jx129Sve back-ground. Mice were housed in a controlled-temperature envi- ronment with a 12-h light/dark cycle. All experiments were performed on male mice except when examining mice on postnatal day 8 (P8) mice, when both. Jackson Laboratory to be integrated into mouse chromosome 16 (C. Lutz, The Jackson Laboratory, personal communication). From this founder mouse, we established a new line of GAA-repeat-expansion-containing FXN YAC transgenic mice on a predominantly C57BL6.

Chronic Tumor Necrosis Factor- Infusion in Gravid C57BL6/J Mice Accelerates Adipose Tissue Development in Female Offspring Suzan Lambin, MSc, Rita van Bree, MLT. ORIGINAL RESEARCH Evaluation of neuropathological effects of a high-fat high-sucrose diet in middle-aged male C57BL6/J mice Bradley J. Baranowski, Kirsten N. Bott.

C57BL/6 Mouse from Charles River Laboratories - selectscience

Eight-week-old male wildtype C57Bl/6 mice (Jackson Laboratory) were used for analysis of miRNA expression changes BMS-907351 chemical structure after 2/3 PH The C57BL/6 mouse is the most widely used strain in mouse research, but did you know there is no standard B6 strain? Learning the characteristics and potential of each B6 substrain will inform more effective study design in metabolism, obesity, diabetes, immunology, behavior, and oncology

Laboratory Mice and Rats - Validated Antibody Database

They are the most widely used and best-selling mouse strain, due to the availability of congenic strains, easy breeding, and robustness. 其实没什么区别 C57BL/6J 就是指的就是在Jackson Laboratory繁育的C57BL/ fancy mouse East asian fancy mouse Laboratory strains 1 M années 2000 ans 100 ans. 5 M.A. 0 0,23 0,35 1,10 1,75 2,40 domesticus musculus molossinus castaneus bactrianus M. spicilegus M. macedonicus M. spretus M. caroli M. cooki M. cervicolor M. musculus. Laboratory Animals Retrospective Study of Spontaneous Osteosarcomas in the Nonobese Diabetic Strain and Nonobese Diabetic-Derived Substrains of Mice [57 Pages Report] Knock out Mice Model report categories the Global market by Indication, Mouse type, End users, Discounting, Corporate Agreements, Economic Model of Demand and Supply, Physiological Characteristics, Business Models, and Stakeholder Analysi Researchers can use Transgenic Core laboratory space and resources side by side with staff members. Consultation in all phases of genome editing (CRISPR/Cas9), transgenic and gene targeting research from experimental design to mouse breeding is freely available. The Core's mission is to provide access to a complex technology so that investigators can focus their resources on research instead.

Animal and Phenotyping Core agingmice

Danciger M, Lyon J, Worrill D, LaVail MM, Yang H (2003) A strong and highly significant QTL on chromosome 6 that protects the mouse from age-related retinal degeneration Introduction of C57BL6 mouse C57BL是小鼠中使用最广泛的品系之一,为了解该品系对于科学选用至关重要。 C57BL中的BL是英文Black(黑色)的缩写,即该品系小鼠与其他品系小鼠外观最大区别是黑色

MGI - Inbred Strains: C57BL - Mouse Genome Informatic

The Jackson Laboratory. University of New Hampshire . University of New Hampshire. 500+ connections. View Kristen Onos' full profile. It's free! Your colleagues, classmates, and 500 million other professionals are on LinkedIn. Join LinkedIn Summary. My. Mice were bred and maintained in the Research Animal Facility at The Jackson Laboratory with free access to food (NIH31 diet with 6% fat) and water on a 12 h light:12 h darkness cycle. All animal studies were performed with the approval of The Jackson Laboratory Animal Care and Use Committee. Male C57BL6/J (B6) mice (10-12 weeks old) were used as normoglycemic controls as describe The Jackson Laboratory Pregnant C57BL6/J mice consumed drinking water containing 0, 8, 25, or 80 ppm sodium arsenite from the fourth day of gestation until birth. Arsenic produced a range of behavioral impairments in male and female offspring at each. To use a different mouse model of MC deficiency, Kit W-sh /Kit W-sh mice were generated from breeder mice obtained from The Jackson Laboratory. B6.Cg-Kit W-sh /HNihrJaeBsmJ females were crossed with C57BL/6J males

Health Evaluation of Experimental Laboratory Mice

The laboratory mouse (Mus musculus) is an excellent tool to define the physiological parameters related to growth processes and to study the effects of genetic and nongenetic factors on a variety of metabolic events Nos3tm1Unc male mice (n 10; RK-eNOS KO; Jackson Laboratory, Bar Harbor, ME) weighing 20-25 g underwent a right subcapsular nephrectomy and surgical resection of the poles of the left kidney Four-week- and eight-week-old virus-free C57BL/6 mice were purchased from the Jackson Laboratory (Bar Harbor, ME, USA). All animal procedures and care were conducted in accordance with ethical guidelines approved by the Institutional Animal Care and Use Committee and B cells from C57Bl6 mice lacking Zbtb32 similarly dis- obtained from The Jackson Laboratory, Bar Harbor ME, and (Jackson Immunoresearch cat#111-035-003) at a dilution of 1:5,000 dilution at 1 hour at 25°C It appeared that BL6Jax DNA (C57BL/6J provided by Jackson Laboratory, Bar Harbor, ME) was not affected by the deletion. This is in contrast to BL6JHUK DNA (C57BL/6J from Harlan, Bicester, UK) (Figs. 2B and 2C )

At what age are laboratory mice considered adult

C57Bl6 mice (N>10). Wild-type (WT) littermates were used as con-trols. Generation of homozygous LDLR−/− mice were obtained from Jackson Laboratory, Bar Harbor, ME. All mice were fed ad libitum and housed at constant ambient temperature in 12-hou. C57BL6/J mice from The Jackson Laboratory (Bar Harbor, ME, USA) were used throughout the study. Mice null for the α7 subunits (The Jackson Laboratory) and their wild-type (WT) littermates were bred in an animal care facility at Vir-ginia Commonwealth Uni. Nicotinic receptors regulate the dynamic range of dopamine release in vivo Jessica L. Koranda,1 Jackson J. Cone,5 Daniel S. McGehee,1,3 Mitchell F. Roitman, 1552 Journal of Lipid Research Volume 52, 2011 Animals C57BL6 mice were from the Jackson Laboratory (Bar Harbor, ME). The Institutional Animal Care and Use Committee.

The Jackson Laboratoryから2002年に日本チャールス・リバー(株)に導入し、供給を開始しました。日本 日本 チャールス・リバー(株)から生産・供給されておりますJAX® Miceは、米国ジャクソン研究所のJAX® Miceです Male mice of the C57Bl6 and A/J strains, and certified double knockout IL-10 null mutants (IL-10-/-) mice (B6.129P2-IL-10<tmlCgn> on a C57Bl6 background) (Jackson Laboratories) were housed in a specific pathogen-free (SPF)-barrier facility in the Division of Laboratory Animal Resources Central Animal Facility, at the University of Pittsburgh Se Kristen Onos profil på LinkedIn, världens största yrkesnätverk. Kristen har angett 3 jobb i sin profil. Se hela profilen på LinkedIn, upptäck Kristens. S1 . Electronic Supplementary Information for. A Fluorescent Probe for the Rapid Detection of Hydrogen Sulfide in Blood Plasma and Brain Tissues in Mice

C57Bl6/J wild type mice (The Jackson Laboratory, Bar Harbor, ME) housed under standard conditions and a 12:12 dark: light cycle were time mated approximately 1 hour prior to the onset of the dark cycle and were checked for presence of a vaginal plug the followin The Jackson Laboratory. University of New Hampshire . University of New Hampshire. 500+ Kontakte. Sehen Sie sich Kristen Onos' vollständiges Profil an. Völlig kostenlos. Ihre Kollegen, Kommilitonen und 500 Millionen weitere Fach- und Führungskräfte. C57BL/6J Jackson Laboratory C57BL/6JMs \'g4G Û%Ê'2 d C57BL/6JJcl ¥ G=GzG0C57BL/6JNrs : U)z Û)r %Ê'2 d C57BL/6JJmsSlc ¥ G6GGG6GyGEG C57BL/6NJcl ¥ G=GzG0 C57BL/6NCrlCrlj ¥ GOGqG GyGGG GxG^G C57BL/6NCrl ¥ GOGqG GyGGG GxG^. This will identify the mice as a C57BL inbred mouse strain from subgroup 6 that was previously bred at The Jackson Laboratory but has since been maintained at the ARC Institute for 20 generations (F20) The transfer of bm12 lymphocytes into a C57BL/6 recipient is an established model of systemic lupus erythematosus. Here we describe how to initiate disease using this model and how to characterize T follicular helper cells, germinal center B cells and plasma cells by flow cytometry